Non-invasive infant meningitis screening, diagnosis and monitoring

Kriba has developed a non-invasive and automatic transfontanellar cerebrospinal fluid white blood cell counter for newborns and infants meningitis screening and monitoring, to reduce negative lumbar punctures and democratize access to early detection around the world.

This is an investigational device. It is not for sale. The claims made on this website have not been evaluated by the FDA or the CE Mark authorities.

OUR MISSION

Kriba generates impact on healthcare worldwide by accelerating non-invasive screening, diagnosis and monitoring of infant meningitis

Meningitis suspicion is challenging due to unspecific signs of the infection, such as fever of an unknown source, especially in infants and newborns who are the most vunerable, and may exhibit minimal symptomatology. 

History and physical examination alone are often insufficient to confirm or exclude the diagnosis of infant meningitis. Lumbar puncture, the current gold standard procedure for screening is invasive, can be difficult to perform and may carry some risk.

Neosonics© non-invasively counts white blood cells in cerebrospinal fluid below the infant fontanelle, offering a quick, easy, and cost-effective way to confirm or rule out suspicion of infant meningitis. In high-income countries with low incidence of the disease, Neosonics© reduces negative lumbar punctures to only positive cases, sparing most suspected patients from the invasive procedure.

Routine lumbar punctures for infant meningitis screening turn out negative in most cases, and results are frequently delayed due to contamination with blood.

In low-income settings with high meningitis burden and limited resources, Neosonics© will help reduce misdiagnosis, mortality, and morbidity rates. The device may present as the only alternative to provide timely intervention for infant meningitis screening and treatment monitoring.

Cost-
efficient

Cost- efficient

It will save costs associated to hospitalization, negative lumbar punctures, laboratory tests and antibiotic treatment.

Sensitivity and accuracy

High sensitivity and specificity to accurately screen, diagnose and monitor, especially for patients with nonspecific clinical presentations.

Single non-
expert user

Single non-expert user

No expertise and minimum specialization required to perform screening and measurements in less than a minute.

Sensitivity
and accuracy

High sensitivity and specificity to accurately screen, diagnose and monitor, especially for patients with nonspecific clinical presentations.

Single non-
expert user

No expertise required, less specialized professionals can perform screening, and measurements take less than a minute.

Cost-
efficient

It will save 40-60% of costs associated
to unnecessary lumbar punctures,
laboratory tests, antibiotics.

Treatment
monitoring

Because it is non-invasive, it can be used to perform frequent measurements to track cerebrospinal fluid white blood cell count evolution, to monitor the patient’s response

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Neosonics

Portable device

Quick & easy to
use in 3 steps

Place

Place Neosonics on the infant’s
fontanel, the head area where
bones are not yet closed

Press

Push the button to get the
cerebrospinal fluid white
blood cell count

Non-invasive
screening

Detect

Detect abnormal cerebrospinal fluid
white blood cell count to immediatly
trigger medication or to follow-up
patient’s response to treatment

Accurate white
blood cell count
results in 30 sec.

Detect

Detect abnormal cerebrospinal fluid
white blood cell count to immediatly
trigger medication or to follow-up
patient’s response to treatment

Scientific Publications

Meningitis Research Foundation Conference

2023

Meningitis screening in young infants based on a novel, non-invasive, transfontanellar ultrasound device: a proof-of-concept study

Sara Ajanovic, Beatrice M. Jobst, et al.

Go to PDF

Meningitis Research Foundation Conference

2023

Cost-effectiveness analysis of implementing a non-invasive screening tool (Neosonics) for meningitis among newborns in Mozambique, Morocco and Spain.

Céline Aerts, Sara Ajanovic, et al.

Go to PDF

Kriba Newborn

Introducing non-invasive infant meningitis screening, diagnosis, and monitoring.

Non-invasive infant meningitis screening, diagnosis and monitoring

OUR MISSION

Kriba generates impact on healthcare worldwide by accelerating non-invasive screening, diagnosis and monitoring of infant meningitis

Meningitis suspicion is challenging due to unspecific signs of the infection, such as fever of an unknown source, especially in infants and newborns who are the most vunerable, and may exhibit minimal symptomatology.

Cost-
efficient

Cost- efficient

Sensitivity and accuracy

Single non-
expert user

Single non-expert user

Sensitivity
and accuracy

Single non-
expert user

Cost-
efficient

Treatment
monitoring

Neosonics

Portable device

Quick & easy to
use in 3 steps

Non-invasive
screening

Accurate white
blood cell count
results in 30 sec.

Scientific Publications

Kriba Newborn

Kriba Newborn

Stay in touch

WARNING

Are you a healthcare
professional?

Non-invasive infant meningitis screening, diagnosis and monitoring

OUR MISSION

Kriba generates impact on healthcare worldwide by accelerating non-invasive screening, diagnosis and monitoring of infant meningitis

Meningitis suspicion is challenging due to unspecific signs of the infection, such as fever of an unknown source, especially in infants and newborns who are the most vunerable, and may exhibit minimal symptomatology.

Cost- efficient

Cost- efficient

Sensitivity and accuracy

Single non-expert user

Single non-expert user

Sensitivity and accuracy

Single non-expert user

Cost- efficient

Treatment monitoring

Neosonics

Portable device

Quick & easy to use in 3 steps

Non-invasive screening

Accurate white blood cell count results in 30 sec.

Scientific Publications

Meningitis Research Foundation Conference

Meningitis Research Foundation Conference

Kriba Newborn

Kriba Newborn

WARNING

Are you a healthcare professional?

Meningitis suspicion is challenging due to unspecific signs of the infection, such as fever of an unknown source, especially in infants and newborns who are the most vunerable, and may exhibit minimal symptomatology. 

Cost-
efficient

Single non-
expert user

Sensitivity
and accuracy

Single non-
expert user

Cost-
efficient

Treatment
monitoring

Quick & easy to
use in 3 steps

Non-invasive
screening

Accurate white
blood cell count
results in 30 sec.

Are you a healthcare
professional?